In 2017, it was not possible to purchase Primatene Mist as it was completely unavailable on the market. The original version of the inhaler was discontinued and removed from shelves on , because it used chlorofluorocarbons (CFCs) as a propellant, which were banned for their role in ozone layer depletion.

Today, Primatene products are widely available at major retailers and pharmacies without a prescription. Why Primatene Mist May Not be the Best Medicine - AAAAI

While the inhaler was unavailable in 2017, the manufacturer, Amphastar Pharmaceuticals, was working on a reformulated version using an environmentally friendly hydrofluoroalkane (HFA) propellant. This new version did not receive FDA approval for over-the-counter (OTC) sale until . Where to Buy Primatene Today