Choosing the right condom involves balancing protection needs, material sensitivities, and desired sensations. For most people, a is the most reliable and affordable choice for preventing both pregnancy and STIs. 1. Material Options STI Protection? Lube Compatibility Latex Overall reliability and affordability Water- or silicone-based only Polyisoprene Latex allergies; "skin-like" feel Water- or silicone-based Polyurethane Latex allergies; ultra-thin feel Any (water, silicone, or oil) Lambskin Maximum heat transfer and natural feel No (porous to viruses) 2. Finding the Right Fit Condom Size Guide: What Size Condom Do I Need? - Hims