: Transfer phosphate groups (typically from ATP) to substrates, a process essential for cell signaling and metabolic regulation. Aminotransferases (EC 2.6) : Transfer amino groups ( −NH2negative cap N cap H sub 2
), critical for DNA methylation and gene expression regulation. transferase
A−X+B→A+B−Xcap A minus cap X plus cap B right arrow cap A plus cap B minus cap X is the donor, is the functional group, and is the acceptor. Primary Subclasses : Transfer phosphate groups (typically from ATP) to
) between an amino acid and a keto acid, playing a key role in amino acid metabolism. : Transfer methyl groups ( −CH3negative cap C cap H sub 3 Primary Subclasses ) between an amino acid and
: Transfer sugar moieties to form glycosidic bonds, which are essential for synthesizing blood group antigens and modifying drug stability.
Transferases are found throughout the cell, with high concentrations in the cytosol, mitochondria, and Golgi bodies. Molecule of the Month: Glutathione Transferases - PDB-101