: The episode contains "lawyer-friendly" references to real-world science, such as "Lipofectamax 9000," a nod to the actual transfection reagent Lipofectamine 2000 .

: Kanji’s obsession with medical research stems from losing his younger sister to an incurable brain tumor years prior.

: The episode has even been the subject of linguistic and cultural studies, such as this Indonesian journal article analyzing the use of polite language (Keigo) in the series.