Lisa reveals she was working on a nanotechnology project called "Project H," which involved injecting nanomachines into human subjects.

Shortly after, Lisa panics, warning that "He" is coming back. She writes a keypad code on the player's arm before fleeing.

The player breaks free and navigates the hospital corridors, dodging the axe-wielding killer. They find an earpiece on a body that allows them to maintain contact with Lisa.

Hysteria Project 2 for PSN (PlayStation Mini) is a first-person survival horror game that continues the narrative of an unnamed man fleeing a persistent hooded, axe-wielding killer . The game uses Full Motion Video (FMV) and interactive segments to tell its story.

A woman identifying herself as a scientist (later revealed as Professor Lisa Spencer ) tells the player they are exhausted and administers an injection.