Meredith Grey transitions into a tough attending, earning the nickname "Medusa" from the new interns.
The surgeons fight to save Seattle Grace Mercy West from bankruptcy, eventually buying the hospital and renaming it Grey Sloan Memorial Hospital in honor of their fallen friends.
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Dr. Bailey faces a devastating MRSA infection scandal that causes her to lose confidence in the OR.
Dr. Yang briefly leaves Seattle for a fellowship at the Mayo Clinic, where she forms a touching bond with Dr. Craig Thomas.
The season marks significant shifts for fan-favorite couples, including April and Jackson’s complex dynamic and the start of Alex and Jo's relationship.