: When medication is necessary, it should be prescribed at the lowest dose that remains effective for the mother to minimize exposure.
: Treatment should be tailored to the specific stage of pregnancy or the age and feeding frequency of the infant. Pregnancy Considerations Drugs in Pregnancy and Lactation
: Most drugs cross the placenta via passive diffusion. Factors increasing transfer include low molecular weight ( Timing of Exposure : : When medication is necessary, it should be
The management of medication during pregnancy and lactation is a complex "balancing act" that weighs the therapeutic needs of the mother against the potential risks to the developing fetus or nursing infant. Because nearly 90% of women take at least one medication during pregnancy, understanding these risks is essential for safe maternal and neonatal care. Factors increasing transfer include low molecular weight (
: For women with chronic conditions, a review of medications 3–6 months before conception is ideal to transition to safer alternatives.