ndocrinopathy (hormone abnormalities, such as hypothyroidism or diabetes) M onoclonal protein (abnormal antibody production) S kin changes (such as darkening or thickening) Key Details About POEMS Syndrome:
It is often delayed, as patients are sometimes misdiagnosed with chronic inflammatory demyelinating polyneuropathy (CIDP). Download Syndrome POEMS pdf
The acronym stands for the five major features of the syndrome: olyneuropathy (nerve damage) O rganomegaly (enlarged liver, spleen, or lymph nodes) POEMS Syndrome - Symptoms, Causes, Treatment | NORD
While there is no standard cure, treatment includes radiation therapy, chemotherapy, and hematopoietic cell transplantation (stem cell transplant). POEMS Syndrome - Symptoms
Search on PubMed or ResearchGate for "POEMS Syndrome Review PDF". POEMS Syndrome - Symptoms, Causes, Treatment | NORD
The exact cause is unknown, but it is linked to an underlying plasma cell dyscrasia (a disorder of the immune system).