: STAT dimers translocate to the nucleus to regulate gene expression. Basic Mechanisms of JAK Inhibition - PMC - NIH
: STAT proteins bind to these sites and are themselves phosphorylated by JAKs. Download Les inhibiteurs JAK STAT pdf
: A cytokine binds to its transmembrane receptor. : STAT dimers translocate to the nucleus to
: Activated JAKs phosphorylate the receptor tail, creating docking sites. creating docking sites.