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: Hepatomegaly can also signal more severe conditions such as primary liver cancer (hepatocellular carcinoma), leukemia, or rare genetic storage diseases like Gaucher or Niemann-Pick disease. Diagnostic Resources

If you are looking for clinical guides or educational materials on this topic, several authoritative medical institutions provide detailed PDFs on the evaluation and management of an enlarged liver: Hepatomegaly (Enlarged Liver) - Cleveland Clinic Download HГ©patomГ©galie pdf

Hepatomegaly (Enlarged Liver) Medically Reviewed.Last updated on 03/26/2025. An enlarged liver is a symptom of underlying disease. Cleveland Clinic : Hepatomegaly can also signal more severe conditions