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Modern classification systems, such as those from the and Histiocyte Society , typically divide these disorders into three primary categories:

Histiocytoses are a diverse group of rare disorders characterized by the abnormal accumulation of cells from the mononuclear phagocyte system, including monocytes, macrophages, and dendritic cells. These conditions can affect virtually any organ, with bones and skin being the most common sites. Classification and Major Types Download Histiocytoses pdf