Biochemistry Of Diabetes And Atherosclerosis Apr 2026

The biochemistry linking diabetes and atherosclerosis centers on how elevated blood glucose and insulin resistance trigger systemic inflammation, oxidative stress, and structural damage to blood vessels. Chronic hyperglycemia alters cellular signaling and energy regulation, accelerating the buildup of fatty plaques (atherosclerosis) in the arterial walls. Core Biochemical Mechanisms The Diabetes Mellitus–Atherosclerosis Connection - PMC