The show centers on the , an elite fictional agency created to handle the most complex and intricate high-profile crimes. Unlike traditional police procedurals, Sled emphasizes forensic science, high-tech laboratory analysis, and expert investigation.

By 2022, the show had accumulated thousands of episodes, maintaining high ratings and a dedicated fanbase.

: The series spanned over 15 years within this timeframe, frequently updating its cast and writing team to keep plots "creative and innovative".